03 September,2012 08:19 AM IST | | AFP
England, set 221 for victory, made 224 for four with 20 balls to spare.
Ian Bell top-scored with 88, with Eoin Morgan was 36 not out and Craig Kieswetter, who finished the match with a six off fast bowler Dale Steyn, unbeaten on 21.
Ian Bell
Earlier, South Africa's 220 for eight after losing the toss saw England off-spinner James Tredwell take three wickets for 35 runs in eight overs.
The series concludes in Nottingham on Wednesday.
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Tredwell had kept his place after figures of two for 49 during England's four-wicket win at The Oval on Friday which levelled the five-match series at 1-1. The Kent bowler only got his chance when England rested Graeme Swann for the rest of this series because of a longstanding elbow injury.
Brief scores: South Africa 220-8 in 50 overs (H Amla 45; J Tredwell 3-35) beat England 224-4 in 46.4 overs (I Bell 88, J Trott 48; D Steyn 2-47) by six wickets.u00a0
