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Scientists create CRISPR protein to boost gene editing to treat genetic diseases

The finding led by Dr. Basudeb Maji, from the Bose Institute, an autonomous institute of the Department of Science and Technology (DST), opens a new chapter in the visualisation and tracking of genome engineering

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Image for representational purpose only. Photo Courtesy: File pic

Image for representational purpose only. Photo Courtesy: File pic

Scientists from Kolkata-based Bose Institute have created GlowCas9 -- a CRISPR protein that lights up while performing gene editing -- to help boost treatment of genetic diseases and cancer, said the Ministry of Science and Technology on Wednesday. 

While CRISPR-Cas9 had been designed to cut and correct DNA with accuracy, scientists could not observe Cas9, the molecular surgeon, in living cells in real time, as traditional detection methods relying on fixing or breaking open cells make it impossible to track the process as it unfolds.

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