<p>Bengaluru doctors successfully treated a 32-year-old woman with a rare autoimmune disease amid her pregnancy.&nbsp;</p>
<p>Autoimmune disorders like Factor 13 acquired deficiency can complicate pregnancies, as antibodies generated by the mother may affect foetal development, particularly the heart.</p>
<p>Factor 13 deficiency is exceedingly rare, occurring in approximately 1 in 2-3 million individuals, and requires specialised care.</p>
<p>The patient, Shradha (name changed), faced multiple fertility challenges due to the autoimmune disorders, including ANA (antinuclear antibody), APL (antiphospholipid antibody), and NK cell deficiency.</p>
<p>Despite undergoing multiple treatments like IUI and IVF, she experienced three consecutive miscarriages.</p>
<p>It was during her second miscarriage, that Shradha was diagnosed with the rare condition, which necessitated the use of blood thinners throughout pregnancy.</p>
<p>Shradha's pregnancy journey was fraught with complications, including frequent bleeding episodes. She conceived naturally on her fourth attempt but continued to face challenges, including spontaneous bleeding.</p>
<p>"The rare condition of inhibitors to Factor 13 leads to deficiency. This is not inherited but can develop due to pre-existing autoimmune conditions. Managing pregnancy with Factor 13 deficiency is exceptionally rare, especially when complicated by acquired inhibitors," said Dr. Poornima M Gowda, Consultant Obstetrician and Gynecologist at Cloudnine Hospital, Benagaluru.</p>
<p>The treatment involved regular blood transfusions to maintain stable Factor 13 levels. Despite the challenges, Shradha delivered a baby girl prematurely at 34 weeks.</p>
<p>The baby, now over six months old, is doing well, said Dr. Poornima.</p>
<p>The chances of the baby developing the same problem are minimal, as the condition is not genetic but will be monitored, she added.</p>
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Bengaluru doctors successfully treat woman with rare autoimmune disorder during pregnancy Shradha`s pregnancy journey was fraught with complications

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