A large UPS cargo plane with three people aboard crashed and exploded on Tuesday while taking off from an airport in Louisville, Kentucky, leaving at least three people dead and 11 injured. Those numbers are expected to grow, Kentucky Governor Andy Beshear said. The plane crashed about 5:15 pm (local time) as it was departing for Honolulu from Louisville's Muhammad Ali International Airport, the Federal Aviation Administration said.

Video showed flames on the plane's left wing and a trail of smoke. The plane then lifted slightly off the ground before crashing and exploding in a huge fireball. Video also revealed portions of a building's shredded roof next to the end of the runway.