The first reported blast struck near the offices of Supreme Leader Ayatollah Ali Khamenei, as security forces sealed off surrounding streets

U.S. President Donald Trump announced the beginning of “major combat operations in Iran,” citing concerns over Tehran’s nuclear and missile programs and urging Iranians to challenge their government

Authorities in Tehran shut down key roads and close airspace as additional blasts echo across the city, while neighboring Iraq also suspends flights amid the escalating regional crisis

Air raid sirens sound in Jerusalem as authorities warn of incoming missiles following Israel’s preemptive strike. A man carries two children to safety in Tel Aviv as sirens echo nationwide, with civilians urged to remain close to bomb shelters

Medical teams move patients to a protected parking structure at Sourasky Medical Center after hospitals activate emergency protocols in anticipation of possible missile impacts

People run to take shelter under bridges after siren sounds while flashes and explosions light up the skies over northern Israel as air defense systems intercept incoming Iranian missiles hours after the initial strikes on Tehran

The Al-Aqsa Mosque compound and Dome of the Rock in Jerusalem in Israel appear largely empty as security warnings and missile alerts keep worshippers and visitors away