Researchers have discovered that metformin -- a drug commonly used to treat Type-2 diabetes -- might also be used to treat a specific form of heart failure known as preserved ejection fraction (HFpEF), finds a new study.

In a mice study, published in the Journal of General Physiology, researchers showed that metformin relaxes a key heart muscle protein called titin, allowing the heart to properly fill with blood before pumping it around the body. This improves the animals' capacity for exercise.