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How Alzheimer's disease-causing gene works decoded

In the study, published in Nature Medicine, the team for the first time used human brain cells to model the disease and test new drugs instead of the mouse models

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Scientists have discovered how a primary genetic risk factor for Alzheimer's causes the disease as well as a potential solution to erase the damage caused by it.

While there is no specific gene that directly causes Alzheimer's, having one copy of the apoE4 gene more than doubles a person's likelihood of developing the disease, and having two copies of the gene increases the risk 12-fold.

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