Japanese researchers successfully regenerate bone using stem cells

A team of researchers from Japan has successfully treated spinal fractures in animal models using stem cells from fatty tissueThe team from the Osaka Metropolitan University used stem cells extracted from adipose the bodyrsquos fatty tissue to treat spine fractures in rats similar to those caused by osteoporosis in humansThese cells offer the advantages of being easy to collect even from elderly individuals and causing little stress to the body suggesting a noninvasive way of treating bone diseasesBone regeneration and strength were significantly improved in rats transplanted with the adipose tissue ADSCsThe genes involved in bone formation and regeneration were also activated The study was published in Bone and Joint ResearchldquoThis study has revealed the potential of bone differentiation spheroids using ADSCs for the development of new treatments for spinal fracturesrdquo said Yuta Sawada a student at the varsitys Graduate School of MedicineldquoSince the cells are obtained from fat there is little burden on the body ensuring patient safety This simple and effective method can treat even difficult fractures and may accelerate healingrdquo added Dr Shinji TakahashiOsteoporosis is a disease that causes bones to become brittle and prone to fractures Among osteoporosisrelated fractures compression fractures of the spine known as osteoporotic vertebral fractures are the most common type of fracture and pose a serious problem leading to a need for longterm care and a significant decline in quality of lifeThe team used stem cells which are multipotent meaning that they can be differentiated into many different cell typesThey developed ADSCs into bonedifferentiated spheroids threedimensional spherical clusters and combined it with betatricalcium phosphate a material widely used for bone reconstruction to successfully treat rats with spinal fracturesldquoThis technique is expected to become a new treatment that helps extend the healthy life of patientsrdquo Takahashi saidThis story has been sourced from a third party syndicated feed agencies Midday accepts no responsibility or liability for its dependability trustworthiness reliability and data of the text Midday managementmiddaycom reserves the sole right to alter delete or remove without notice the content in its absolute discretion for any reason whatsoever