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Mumbai docs perform 1st domino kidney transplant of 2025 for sensitised patient

The procedure was essential for patients battling kidney failure and inability to get transplanted due to high risk of rejection with their available family donors

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A domino transplant involves a chain of donors and recipients where each donor matches a different recipient, creating a life-saving chain. Image for representational purpose only. Photo Courtesy: istock

A domino transplant involves a chain of donors and recipients where each donor matches a different recipient, creating a life-saving chain. Image for representational purpose only. Photo Courtesy: istock

Mumbai doctors have successfully performed the city’s first HLA compatible, acceptable mismatch domino kidney transplant of the year. This extraordinary procedure involved six surgeries across hospitals and states, uniting three donors and three recipient families in a synchronised chain to save lives. 

In a landmark medical feat, a multidisciplinary team led by Dr. Bharat Shah, Dr. Shruti Tapiawala, Dr. Pradeep Rao, Dr. Jitendra Jagtap at Gleneagles Hospital, Parel, Mumbai. Leveraging advanced transplant immunodiagnositics and acceptable mismatch techniques in HLA medicine, the domino transplant addressed the unique challenges of highly sensitised patients which is only 7-10 per cent of transplant population, marking a new milestone in renal transplantation for our state and country.

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