Long-term use of artificial sweeteners or low- and no-calorie sweeteners, used mainly by people with diabetes, can lead to cognitive decline, claimed a study. 

Researchers from the Universidade de São Paulo, Brazil, analysed 12,000 patients who use common artificial sweeteners such as aspartame, saccharin, xylitol, erythritol, sorbitol, tagatose, and acesulfame K.