At least four persons were killed when a suspected US drone aircraft fired two missiles at a school in Pakistan's troubled south Waziristan tribal region on Friday, local tribesmen said.

The missiles hit a middle school at Sultana village in south Waziristan at 10 am, they said. Witnesses said tribesmen rushed to the site of the attack and pulled bodies out of the rubble. The school building was destroyed in the attack, they said.