U.S. President Joe Biden on Tuesday appointed top officials from the Federal Emergency Management Agency (FEMA) and the Centers for Disease Control and Prevention (CDC) to coordinate the administration’s response to monkeypox in the United States.

The appointments come as the United States aims to bolster vaccination efforts to slow the spread of a monkeypox outbreak that has infected more than 5,800 Americans. On Monday, California Governor Gavin Newsom declared a state of emergency over monkeypox.