Manchester: Struck by a series of injury setbacks, England will look to get the combination right when they take on the low-ranked but spirited Afghanistan in their bid get closer to a semi-final berth, here on Tuesday.

The hosts are struggling with fitness issues, the latest being captain Eoin Morgan having to leave the field with a back spasm during the game against the West Indies. Opening batsman Jason Roy was also forced off the field during the same match due to a tight hamstring and has been ruled out of the game on Tuesday and Friday (against Sri Lanka). Himself in doubt for the Afghanistan game, Morgan insisted there is no need to hit the panic button just yet. His fitness will be monitored over the next 24 hours before the final call is take on his participation on Tuesday.