Rafael Nadal crashed to his worst Grand Slam defeat in seven years on Thursday when Czech journeyman Lukas Rosol, the world number 100, pulled off one of the greatest upsets in Wimbledon history.

Rosol, whose previous five visits to Wimbledon had ended in first round losses in qualifying, stunned the 2008 and 2010 champion, and 11-time Grand Slam title winner Nadal, 6-7 (9/11), 6-4, 6-4, 2-6, 6-4 in the second round.