Trailblazing Indian tennis star Sania Mirza’s swansong appearance at Wimbledon ended in a semi-final defeat to defending champions Neal Skupski and Desirae Krawczyk in the mixed doubles event here.

Mirza and her Croatian partner Mate Pavic, seeded sixth, went down 6-4, 5-7, 4-6 to Skupski of Great Britain and American Krawczyk on Wednesday night.